Norfloxacin Nicotinic Soluble Powder

Norfloxacin soluble powder

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Norfloxacin Nicotinic Soluble Powder

[Main ingredients] norfloxacin nicotinate

[Character] this product is a kind of white or light yellow crystalline powder.

[Pharmacological action] Pharmacodynamics  Norfloxacin nicotinate is bactericidal broad-spectrum antibacterial drug, on Escherichia coli, Salmonella, Klebsiella pneumoniae, Brucella, Pasteurella multocida, pleura pneumonia put line coli, erysipelas bacillus, proteus, Serratia marcescens, Corynebacterium pyogenes, septicemia Potts bacteria, Staphylococcus aureus, mycoplasma and other have a good effect, Pseudomonas aeruginosa, Streptococcus effect is weak, on anaerobic bacteria action is weak.Better antibacterial activity than nalidixic acid and Pipemidic Acid, but not enrofloxacin.This class of drugs antibacterial mechanism is role in bacterial cell DNA gyrase (type II topoisomerase), interfere with bacterial DNA replication, transcription and recombination repair, bacteria cannot normal growth and reproduction of death.

Pharmacokinetic study  The biological utilization of the product is relatively low, when the chicken is taken orally for 57% ~ 61%., the oral dosage of 1/3 is discharged through urine, 80% of which is the original drug, the half-life of the chicken is 3.7 to 12.1 hours.

[Drug interactions]①With the amino glycosides, broad-spectrum penicillin combination has a synergistic effect.②Ca2+, Mg2+, Fe3+, Ab3 +and other heavy metal ions and the product can occur chelate, affect the absorption.③This class of drugs and theophylline, caffeine and can make the latter's metabolic inhibition, blood theophylline, caffeine concentrations of abnormal rise, and even the emergence of theophylline poisoning symptoms.This product has less effect on theophylline metabolism.

[Indications] for treating chicken bacterial disease and mycoplasma infections, such as Chicken Escherichia coli disease, Salmonella pullorum disease, avian Pasteurellosis, chronic respiratory disease of chickens.

[Usage and dosage] according to the computing mixed drink per liter of water chicken 1.25 ~ 2.5g (norfloxacin nicotinate according to calculation of 125 ~ 250mg) used in conjunction with 3 to 5 days

[Adverse reaction]①The young animal cartilage degeneration, causing lameness and pain.②The digestive system reaction has vomiting, abdominal pain, abdominal distension.③The skin reaction is erythema, itching, urticaria and photosensitive reaction and so on.

[Note] the egg laying period of laying hens is disabled.

[Withdrawal period]Chicken 28 days

[Specification] according to the calculation of 10% norfloxacin nicotinate

[Packing]100g*60 bottle

[Storage] light shading, airtight preservation.